Effects of zoledronic acid on odontoblast-like cells

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Effects of zoledronic acid on odontoblast-like cells.

The aim of the study was to evaluate the effects of a highly potent bisphosphonate, zoledronic acid (ZOL), on cultured odontoblast-like cells MDPC-23. The cells (1.5×10(4)cells/cm(2)) were seeded for 48h in wells of 24-well dished. Then, the plain culture medium (DMEM) was replaced by fresh medium without fetal bovine serum. After 24h, ZOL (1 or 5μM) was added to the medium and maintained in co...

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ژورنال

عنوان ژورنال: Archives of Oral Biology

سال: 2013

ISSN: 0003-9969

DOI: 10.1016/j.archoralbio.2012.09.016